High MTHFR promoter methylation levels in men confer protection against ischemic stroke

The MTHFR gene encodes methylenetetrahydrofolate reductase required for the metabolism of homocysteine (Hcy) – a previously reported independent risk factor for ischemic stroke (IS). In this study, we first aimed to clarify the association between DNA methylation levels in the MTHFR promoter and th...

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Bibliographic Details
Main Authors: Shan Xu, Qianping Shi, Bo Li, Liyuan Han, Guodong Xu, Xiaolin Peng, Hongen Chen, Shuhong Dai, Wancheng Ma, Changyi Wang, Jianping Ma
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2020-11-01
Series:Biomolecules & Biomedicine
Subjects:
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/4636