High MTHFR promoter methylation levels in men confer protection against ischemic stroke

High MTHFR promoter methylation levels in men confer protection against ischemic stroke

The MTHFR gene encodes methylenetetrahydrofolate reductase required for the metabolism of homocysteine (Hcy) – a previously reported independent risk factor for ischemic stroke (IS). In this study, we first aimed to clarify the association between DNA methylation levels in the MTHFR promoter and th...

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Bibliographic Details
Main Authors: Shan Xu, Qianping Shi, Bo Li, Liyuan Han, Guodong Xu, Xiaolin Peng, Hongen Chen, Shuhong Dai, Wancheng Ma, Changyi Wang, Jianping Ma
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2020-11-01
Series:Biomolecules & Biomedicine
Subjects:
Ischemic stroke
MTHFR
methylation
Hcy
hypertension
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/4636

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