Role of BRCA Mutation and HE4 in Predicting Chemotherapy Response in Ovarian Cancer: A Retrospective Pilot Study

Role of BRCA Mutation and HE4 in Predicting Chemotherapy Response in Ovarian Cancer: A Retrospective Pilot Study

Even though 80% of patients with High-Grade Serous Ovarian Cancer respond to standard first-line chemotherapy, a majority of them could relapse in the following five years due to a resistance to platinum. Human Epididymis protein 4 (HE4) is one of the most promising markers in predicting platinum th...

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Bibliographic Details
Main Authors: Francesco Plotti, Corrado Terranova, Federica Guzzo, Carlo De Cicco Nardone, Daniela Luvero, Martina Bartolone, Camilla Dionisi, Domenico Benvenuto, Silvia Fabris, Massimo Ciccozzi, Violante Di Donato, Pierluigi Benedetti Panici, Roberto Angioli
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Biomedicines
Subjects:
ovarian cancer
HE4
<i>BRCA</i>
chemotherapy response
Online Access:https://www.mdpi.com/2227-9059/9/1/55

Internet

https://www.mdpi.com/2227-9059/9/1/55

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