Crystal structure of human peptidylarginine deiminase type VI (PAD6) provides insights into its inactivity

Crystal structure of human peptidylarginine deiminase type VI (PAD6) provides insights into its inactivity

Human peptidylarginine deiminase isoform VI (PAD6), which is predominantly limited to cytoplasmic lattices in the mammalian oocytes in ovarian tissue, is essential for female fertility. It belongs to the peptidylarginine deiminase (PAD) enzyme family that catalyzes the conversion of arginine residue...

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Bibliographic Details
Main Authors: Fanomezana M. Ranaivoson, Rieke Bande, Isabell Cardaun, Antonio De Riso, Annette Gärtner, Pui Loke, Christina Reinisch, Prasuna Vogirala, Edward Beaumont
Format: Article
Language:English
Published: International Union of Crystallography 2024-05-01
Series:IUCrJ
Subjects:
mammalian fertilization
cytoplasmic lattices
human peptidylarginine deiminase vi
protein structures
pad6
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252524002549

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http://scripts.iucr.org/cgi-bin/paper?S2052252524002549

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