Analysis of the effects of spaceflight and local administration of thrombopoietin to a femoral defect injury on distal skeletal sites

Analysis of the effects of spaceflight and local administration of thrombopoietin to a femoral defect injury on distal skeletal sites

Abstract With increased human presence in space, bone loss and fractures will occur. Thrombopoietin (TPO) is a recently patented bone healing agent. Here, we investigated the systemic effects of TPO on mice subjected to spaceflight and sustaining a bone fracture. Forty, 9-week-old, male, C57BL/6 J w...

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Bibliographic Details
Main Authors: Ariane Zamarioli, Zachery R. Campbell, Kevin A. Maupin, Paul J. Childress, Joao P. B. Ximenez, Gremah Adam, Nabarun Chakraborty, Aarti Gautam, Rasha Hammamieh, Melissa A. Kacena
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:npj Microgravity
Online Access:https://doi.org/10.1038/s41526-021-00140-0

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https://doi.org/10.1038/s41526-021-00140-0

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