Targeting Extracellular RNA Mitigates Hepatic Lipotoxicity and Liver Injury in NASH

Targeting Extracellular RNA Mitigates Hepatic Lipotoxicity and Liver Injury in NASH

Non-alcoholic steatohepatitis (NASH) is a clinically serious stage of non-alcoholic fatty liver disease (NAFLD). Histologically characterized by hepatocyte ballooning, immune cell infiltration, and fibrosis, NASH, at a molecular level, involves lipid-induced hepatocyte death and cytokine production....

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Bibliographic Details
Main Authors: Archana Tewari, Sangam Rajak, Sana Raza, Pratima Gupta, Bandana Chakravarti, Jyotika Srivastava, Chandra P. Chaturvedi, Rohit A. Sinha
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cells
Subjects:
damage-associated molecular patterns (DAMPs)
extracellular RNA
lipotoxicity
inflammation
non-alcoholic steatohepatitis (NASH)
Online Access:https://www.mdpi.com/2073-4409/12/14/1845

Internet

https://www.mdpi.com/2073-4409/12/14/1845

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