Tau Avoids the GTP Cap at Growing Microtubule Plus-Ends

Summary: Plus-end tracking proteins (+TIPs) associate with the growing end of microtubules and mediate important cellular functions. The majority of +TIPs are directed to the plus-end through a family of end-binding proteins (EBs), which preferentially bind the stabilizing cap of GTP-tubulin present...

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Bibliographic Details
Main Authors: Brian T. Castle, Kristen M. McKibben, Elizabeth Rhoades, David J. Odde
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220309792