Knockdown of Gene Expression in Macrophages by microRNA Mimic-Containing Poly (Lactic-<i>co</i>-glycolic Acid) Microparticles

<b>Background:</b> microRNA (miRNA) regulate target gene expression through translational repression and/or mRNA degradation and are involved in the regulation of inflammation. Macrophages are key inflammatory cells that are important in chronic inflammatory lung diseases such as cystic...

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Bibliographic Details
Main Authors: Paul J. McKiernan, Patrick Lynch, Joanne M. Ramsey, Sally Ann Cryan, Catherine M. Greene
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Medicines
Subjects:
Online Access:https://www.mdpi.com/2305-6320/5/4/133