Anti-fatigue effect of OM-X, fermented plant extract with lactic acid bacteria and bifidobacteria: A randomized, placebo-controlled, double-blind, comparative study
The objective of this study is to elucidate how the OM-X made from many kinds of plants fermented using lactic acid bacteria (LAB) and bifidobacteria contributes to anti-fatigue. A randomized, placebo-controlled, double-blind, comparative study design was adopted. We investigated the effects of 12-w...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-10-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464622002985 |
| _version_ | 1811264975169126400 |
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| author | Takeshi Kaneko Akinobu Miyata Muneaki Takahata |
| author_facet | Takeshi Kaneko Akinobu Miyata Muneaki Takahata |
| author_sort | Takeshi Kaneko |
| collection | DOAJ |
| description | The objective of this study is to elucidate how the OM-X made from many kinds of plants fermented using lactic acid bacteria (LAB) and bifidobacteria contributes to anti-fatigue. A randomized, placebo-controlled, double-blind, comparative study design was adopted. We investigated the effects of 12-week ingestion of the test food or placebo. Visual analogue scale (VAS) and Chalder fatigue scale (CFS) were examined to evaluate the feeling of fatigue, and diacron-reactive oxygen metabolites (d-ROMs) and Biological Antioxidant Potential (BAP) were measured to appraise comprehensive antioxidative ability. We also evaluated the safety of the food. As a result, significant differences between the two groups were detected in VAS and CFS. No safety-related matter occurred. It turned out that the ingestion of OM-X improved feelings of fatigue for healthy people with temporary fatigue. Additionally, there was no adverse effect by the ingestion of the food. |
| first_indexed | 2024-04-12T20:14:09Z |
| format | Article |
| id | doaj.art-b9800c1115e64a0da0bce1e5b2ee9208 |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-04-12T20:14:09Z |
| publishDate | 2022-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-b9800c1115e64a0da0bce1e5b2ee92082022-12-22T03:18:10ZengElsevierJournal of Functional Foods1756-46462022-10-0197105228Anti-fatigue effect of OM-X, fermented plant extract with lactic acid bacteria and bifidobacteria: A randomized, placebo-controlled, double-blind, comparative studyTakeshi Kaneko0Akinobu Miyata1Muneaki Takahata2Japan Clinical Trial Association (JACTA), 5F, Forecast Shinjuku South Bldg. 4-3-17 Shinjuku, Shinjuku-ku, Tokyo 160-0022, Japan; Corresponding author at: Japan Clinical Trial Association (JACTA), 5F, Forecast Shinjuku South Bldg. 4-3-17 Shinjuku, Shinjuku-ku, Tokyo 160-0022, Japan.Miyata Medical Clinic, 9F, Tokyo Fugetsudo Nihonbshi Bldg. 2-2-8 Nihonbshi, Chuo-ku, Tokyo 103-0027, JapanBIOBANK Co., Ltd., 388-1 Hirata, Kita-ku, Okayama City, Okayama 700-0952, JapanThe objective of this study is to elucidate how the OM-X made from many kinds of plants fermented using lactic acid bacteria (LAB) and bifidobacteria contributes to anti-fatigue. A randomized, placebo-controlled, double-blind, comparative study design was adopted. We investigated the effects of 12-week ingestion of the test food or placebo. Visual analogue scale (VAS) and Chalder fatigue scale (CFS) were examined to evaluate the feeling of fatigue, and diacron-reactive oxygen metabolites (d-ROMs) and Biological Antioxidant Potential (BAP) were measured to appraise comprehensive antioxidative ability. We also evaluated the safety of the food. As a result, significant differences between the two groups were detected in VAS and CFS. No safety-related matter occurred. It turned out that the ingestion of OM-X improved feelings of fatigue for healthy people with temporary fatigue. Additionally, there was no adverse effect by the ingestion of the food.http://www.sciencedirect.com/science/article/pii/S1756464622002985Anti-fatigueFermented plant extractLactic acid bacteriaBifidobacterialChalder fatigue scale |
| spellingShingle | Takeshi Kaneko Akinobu Miyata Muneaki Takahata Anti-fatigue effect of OM-X, fermented plant extract with lactic acid bacteria and bifidobacteria: A randomized, placebo-controlled, double-blind, comparative study Journal of Functional Foods Anti-fatigue Fermented plant extract Lactic acid bacteria Bifidobacterial Chalder fatigue scale |
| title | Anti-fatigue effect of OM-X, fermented plant extract with lactic acid bacteria and bifidobacteria: A randomized, placebo-controlled, double-blind, comparative study |
| title_full | Anti-fatigue effect of OM-X, fermented plant extract with lactic acid bacteria and bifidobacteria: A randomized, placebo-controlled, double-blind, comparative study |
| title_fullStr | Anti-fatigue effect of OM-X, fermented plant extract with lactic acid bacteria and bifidobacteria: A randomized, placebo-controlled, double-blind, comparative study |
| title_full_unstemmed | Anti-fatigue effect of OM-X, fermented plant extract with lactic acid bacteria and bifidobacteria: A randomized, placebo-controlled, double-blind, comparative study |
| title_short | Anti-fatigue effect of OM-X, fermented plant extract with lactic acid bacteria and bifidobacteria: A randomized, placebo-controlled, double-blind, comparative study |
| title_sort | anti fatigue effect of om x fermented plant extract with lactic acid bacteria and bifidobacteria a randomized placebo controlled double blind comparative study |
| topic | Anti-fatigue Fermented plant extract Lactic acid bacteria Bifidobacterial Chalder fatigue scale |
| url | http://www.sciencedirect.com/science/article/pii/S1756464622002985 |
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