Antimicrobial Properties and Cytotoxicity of LL-37-Derived Synthetic Peptides to Treat Orthopedic Infections

Antimicrobial Properties and Cytotoxicity of LL-37-Derived Synthetic Peptides to Treat Orthopedic Infections

Open fractures and prosthetic joints are prone to bacterial infections, especially those involving biofilms, and are worsened by antibiotic inefficacy and resistance. This highlights the need for targeted treatments against orthopedic infections. LL-37, a human cathelicidin, is known for its antimic...

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Bibliographic Details
Main Authors: Vincenzo Pennone, Elisa Angelini, David Sarlah, Arianna B. Lovati
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Antibiotics
Subjects:
synthetic peptides
LL-37
antimicrobial activity
biocompatibility
cytotoxicity
orthopedic infections
Online Access:https://www.mdpi.com/2079-6382/13/8/764

Internet

https://www.mdpi.com/2079-6382/13/8/764

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