Narsoplimab for severe transplant-associated thrombotic microangiopathy
Abstract Background Transplantation-associated thrombotic microangiopathy (TA-TMA) is an endothelial injury syndrome linked to the overactivation of complement pathways. It manifests with microangiopathic hemolytic anemia, consumptive thrombocytopenia, and microvascular thrombosis leading to ischemi...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-03-01
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Series: | Thrombosis Journal |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12959-023-00464-9 |