Normal Proteasome Function Is Needed to Prevent Kidney Graft Injury during Cold Storage Followed by Transplantation

Normal Proteasome Function Is Needed to Prevent Kidney Graft Injury during Cold Storage Followed by Transplantation

Kidney transplantation is the preferred treatment for end-stage kidney disease (ESKD). However, there is a shortage of transplantable kidneys, and donor organs can be damaged by necessary cold storage (CS). Although CS improves the viability of kidneys from deceased donors, prolonged CS negatively a...

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Bibliographic Details
Main Authors: Dinesh Bhattarai, Seong-Ok Lee, Lee Ann MacMillan-Crow, Nirmala Parajuli
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
cold storage and transplantation
proteasome subunits Rpt6 and B5
proteasome dysfunction
proteasome assembly chaperone PAC1
bortezomib
Online Access:https://www.mdpi.com/1422-0067/25/4/2147

Internet

https://www.mdpi.com/1422-0067/25/4/2147

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