Genome-wide methylation analysis identifies a core set of hypermethylated genes in CIMP-H colorectal cancer

Genome-wide methylation analysis identifies a core set of hypermethylated genes in CIMP-H colorectal cancer

Abstract Background Aberrant DNA methylation profiles are a characteristic of all known cancer types, epitomized by the CpG island methylator phenotype (CIMP) in colorectal cancer (CRC). Hypermethylation has been observed at CpG islands throughout the genome, but it is unclear which factors determin...

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Bibliographic Details
Main Authors: Tyler McInnes, Donghui Zou, Dasari S. Rao, Francesca M. Munro, Vicky L. Phillips, John L. McCall, Michael A. Black, Anthony E. Reeve, Parry J. Guilford
Format: Article
Language:English
Published: BMC 2017-03-01
Series:BMC Cancer
Subjects:
Epigenome
Methylation
Colorectal cancer
CIMP
Online Access:http://link.springer.com/article/10.1186/s12885-017-3226-4

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http://link.springer.com/article/10.1186/s12885-017-3226-4

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