Improved leptin sensitivity as a potential candidate responsible for the spontaneous food restriction of the Lou/C rat.

The Lou/C rat, an inbred strain of Wistar origin, was described as a model of resistance to age- and diet-induced obesity. Although such a resistance involves many metabolic parameters described in our previous studies, Lou/C rats also exhibit a spontaneous food restriction due to decreased food con...

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Bibliographic Details
Main Authors: Christelle Veyrat-Durebex, Anne-Laure Poher, Aurélie Caillon, Emmanuel Somm, Philippe Vallet, Yves Charnay, Françoise Rohner-Jeanrenaud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24039946/pdf/?tool=EBI