Second passage experiments of chronic wasting disease in transgenic mice overexpressing human prion protein

Second passage experiments of chronic wasting disease in transgenic mice overexpressing human prion protein

Abstract Chronic wasting disease (CWD) is a prion disease of cervids including deer, elk, reindeer, and moose. Human consumption of cervids is common, therefore assessing the risk potential of CWD transmission to humans is critical. In a previous study, we tested CWD transmission via intracerebral i...

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Bibliographic Details
Main Authors: Brent Race, Chase Baune, Katie Williams, James F. Striebel, Andrew G. Hughson, Bruce Chesebro
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Veterinary Research
Subjects:
RT-QuIC
prion
cross-species transmission
barrier
chronic wasting disease
transgenic mice
Online Access:https://doi.org/10.1186/s13567-022-01130-0

Internet

https://doi.org/10.1186/s13567-022-01130-0

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