Nuciferine prevents hepatic steatosis associated with improving intestinal mucosal integrity, mucus-related microbiota and inhibiting TLR4/MyD88/NF-κB pathway in high-fat induced rats

Nuciferine prevents hepatic steatosis associated with improving intestinal mucosal integrity, mucus-related microbiota and inhibiting TLR4/MyD88/NF-κB pathway in high-fat induced rats

Nonalcoholic fatty liver disease (NAFLD) has been demonstrated to be closely associated with intestinal barrier functions. The aim of this study is to investigate the effects of nuciferine on preventing hepatic steatosis with relation to intestinal barrier functions in HFD-fed rats. The results show...

Full description

Bibliographic Details
Main Authors: Jiemin Fan, Jingyue Sun, Tingting Li, Xiaoxue Yan, Yihong Jiang
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Journal of Functional Foods
Subjects:
Nuciferine
Hepatic steatosis
Intestinal mucosal integrity
Akkmensia muciniphila
TLR4/MyD88/NF-κB
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464621005089

Internet

http://www.sciencedirect.com/science/article/pii/S1756464621005089

Similar Items