Elevated PLAUR is observed in the airway epithelium of asthma patients and blocking improves barrier integrity
Abstract Background Expression of the urokinase plasminogen activator receptor (uPAR) is elevated in the airway epithelium in asthma; however, the contribution of uPAR to asthma pathogenesis and scope for therapeutic targeting remains unknown. Objectives To determine (i) the expression profile of uP...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-10-01
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Series: | Clinical and Translational Allergy |
Subjects: | |
Online Access: | https://doi.org/10.1002/clt2.12293 |