Association of the prefrailty with global brain atrophy and white matter lesions among cognitively unimpaired older adults: the Nakajima study

Association of the prefrailty with global brain atrophy and white matter lesions among cognitively unimpaired older adults: the Nakajima study

Abstract Physical frailty has been associated with adverse outcomes such as dementia. However, the underlying structural brain abnormalities of physical frailty are unclear. We investigated the relationship between physical frailty and structural brain abnormalities in 670 cognitively unimpaired ind...

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Bibliographic Details
Main Authors: Moeko Noguchi-Shinohara, Kenjiro Ono, Sohshi Yuki-Nozaki, Kazuo Iwasa, Masami Yokogawa, Kiyonobu Komai, Benjamin Thyreau, Yasuko Tatewaki, Yasuyuki Taki, Mao Shibata, Tomoyuki Ohara, Jun Hata, Toshiharu Ninomiya, Masahito Yamada
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-16190-7

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https://doi.org/10.1038/s41598-022-16190-7

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