Optical analysis of AMPAR-mediated synaptic scaling in mouse hippocampus

Summary: Immunolabeling of surface AMPA receptors (AMPARs) can be used for in vivo or ex vivo examination of synaptic scaling, a type of homeostatic plasticity. Here, we present a protocol to analyze changes in synaptic weights using immunohistochemistry for surface AMPARs coupled with optical imagi...

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Bibliographic Details
Main Authors: Kanzo Suzuki, Ege T. Kavalali, Lisa M. Monteggia
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722003239