Pharmacological Screening of Kv7.1 and Kv7.1/KCNE1 Activators as Potential Antiarrhythmic Drugs in the Zebrafish Heart

Pharmacological Screening of Kv7.1 and Kv7.1/KCNE1 Activators as Potential Antiarrhythmic Drugs in the Zebrafish Heart

Long QT syndrome (LQTS) can lead to ventricular arrhythmia and sudden cardiac death. The most common congenital cause of LQTS is mutations in the channel subunits generating the cardiac potassium current <i>I</i><sub>Ks</sub>. Zebrafish (<i>Danio rerio</i>) have b...

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Bibliographic Details
Main Authors: Alicia De la Cruz, Xiaoan Wu, Quinn C. Rainer, Irene Hiniesto-Iñigo, Marta E. Perez, Isak Edler, Sara I. Liin, H. Peter Larsson
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
<i>I</i><sub>Ks</sub>
long QT syndrome
polyunsaturated fatty acids
zebrafish heart
ML-277
Online Access:https://www.mdpi.com/1422-0067/24/15/12092

Internet

https://www.mdpi.com/1422-0067/24/15/12092

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