Exploring the immunomodulatory role of virtual memory CD8+ T cells: Role of IFN gamma in tumor growth control

Exploring the immunomodulatory role of virtual memory CD8+ T cells: Role of IFN gamma in tumor growth control

Virtual memory CD8+ T cells (TVM) have been described as cells with a memory-like phenotype but without previous antigen (Ag) exposure. TVM cells have the ability to respond better to innate stimuli rather than by TCR engagement, producing large amounts of interferon gamma (IFNγ) after stimulation w...

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Bibliographic Details
Main Authors: Constanza Savid-Frontera, Maria Estefania Viano, Natalia S. Baez, Nicolas L. Lidon, Quentin Fontaine, Howard A. Young, Lene Vimeux, Emmanuel Donnadieu, Maria Cecilia Rodriguez-Galan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
virtual memory CD8+ T cells
cancer
IL-12
IL-18
IFNg
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.971001/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.971001/full

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