Cohesin interaction with centromeric minichromosomes shows a multi-complex rod-shaped structure.

Cohesin is the protein complex responsible for maintaining sister chromatid cohesion. Cohesin interacts with centromeres and specific loci along chromosome arms known as Chromosome Attachment Regions (CARs). The cohesin holocomplex contains four subunits. Two of them, Smc1p (Structural maintenance o...

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Bibliographic Details
Main Authors: Alexandra Surcel, Douglas Koshland, Hong Ma, Robert T Simpson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2408725?pdf=render