Systematic investigation of the impact of screw elements in continuous wet granulation

Systematic investigation of the impact of screw elements in continuous wet granulation

Twin-screw wet granulation (TSG) is a continuous manufacturing technique either for granules as final dosage form or as an intermediate before tableting or capsule filling. A comprehensive process understanding is required to implement TSG, considering various parameters influencing granule and tabl...

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Bibliographic Details
Main Authors: Katharina Kiricenko, Robin Meier, Peter Kleinebudde
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Continuous manufacturing
Twin-screw wet granulation
Screw configuration
Design of experiments
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156724000458

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http://www.sciencedirect.com/science/article/pii/S2590156724000458

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