Acute Induction of Translocon-Mediated Ca<sup>2+</sup> Leak Protects Cardiomyocytes Against Ischemia/Reperfusion Injury

Acute Induction of Translocon-Mediated Ca<sup>2+</sup> Leak Protects Cardiomyocytes Against Ischemia/Reperfusion Injury

During myocardial infarction, dysregulation of Ca<sup>2+</sup> homeostasis between the reticulum, mitochondria, and cytosol occurs in cardiomyocytes and leads to cell death. Ca<sup>2+</sup> leak channels are thought to be key regulators of the reticular Ca<sup>2+</su...

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Bibliographic Details
Main Authors: Ribal Al-Mawla, Mallory Ducrozet, Nolwenn Tessier, Lucille Païta, Bruno Pillot, Yves Gouriou, Camille Villedieu, Zeina Harhous, Alexandre Paccalet, Claire Crola Da Silva, Michel Ovize, Gabriel Bidaux, Sylvie Ducreux, Fabien Van Coppenolle
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
Ca<sup>2+</sup> leak channel
translocon
reticulum
cardioprotection
ischemia-reperfusion
Online Access:https://www.mdpi.com/2073-4409/9/5/1319

Internet

https://www.mdpi.com/2073-4409/9/5/1319

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