The Role of Toll-like Receptors in Colorectal Cancer Progression: Evidence for Epithelial to Leucocytic Transition (ELT)

Toll-like receptors (TLRs) are expressed by immune cells, intestinal epithelium, and tumor cells. In the homeostatic setting they help to regulate control over invading pathogens and maintain the epithelial lining of the large and small intestines. Aberrant expression of certain TLRs by tumor cells...

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Bibliographic Details
Main Authors: Kimberly A Luddy, Mark eRobertson-Tessi, Narges eTafreshi, Hatem eSoliman, David L. Morse
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00429/full