<named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> MmsA (Rv0753c) Interacts with STING and Blunts the Type I Interferon Response

<named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> MmsA (Rv0753c) Interacts with STING and Blunts the Type I Interferon Response

ABSTRACT Type I interferon (IFN) plays an important role in Mycobacterium tuberculosis persistence and disease pathogenesis. M. tuberculosis has evolved a number of mechanisms to evade host immune surveillance. However, it is unclear how the type I IFN response is tightly regulated by the M. tubercu...

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Bibliographic Details
Main Authors: Yifan Sun, Wei Zhang, Chunsheng Dong, Sidong Xiong
Format: Article
Language:English
Published: American Society for Microbiology 2020-12-01
Series:mBio
Subjects:
STING
Mycobacterium tuberculosis
type I IFN
MmsA (Rv0753c)
p62
selective autophagy
Online Access:https://journals.asm.org/doi/10.1128/mBio.03254-19

Internet

https://journals.asm.org/doi/10.1128/mBio.03254-19

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