CagA orchestrates eEF1A1 and PKCδ to induce interleukin-6 expression in Helicobacter pylori-infected gastric epithelial cells

Abstract Background Helicobacter pylori colonises the stomach of approximately 50% of the global population. Cytotoxin-associated gene A protein (CagA) is one of the important virulent factors responsible for the increased inflammation and increases the risk of developing peptic ulcers and gastric c...

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Bibliographic Details
Main Authors: Shaohan Xu, Xiaoqian Wu, Xiaoyan Zhang, Chu Chen, Hao Chen, Feifei She
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Gut Pathogens
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13099-020-00368-3