Dissection of paracrine/autocrine interplay in lung tumor microenvironment mimicking cancer cell-monocyte co-culture models reveals proteins that promote inflammation and metastasis

Dissection of paracrine/autocrine interplay in lung tumor microenvironment mimicking cancer cell-monocyte co-culture models reveals proteins that promote inflammation and metastasis

Abstract Background Tumor cell-monocyte interactions play crucial roles in shaping up the pro-tumorigenic phenotype and functional output of tumor-associated macrophages. Within the tumor microenvironment, such heterotypic cell–cell interactions are known to occur via secretory proteins. Secretory p...

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Bibliographic Details
Main Authors: Asif Amin, Aabid Mustafa Koul, Umer Majeed Wani, Faizah Farooq, Basit Amin, Zubair Wani, Asif Lone, Ayub Qadri, Raies A. Qadri
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Cancer
Subjects:
Tumor microenvironment
Tumor associated macrophages
Inflammation
Secretome
Metastasis
Online Access:https://doi.org/10.1186/s12885-023-11428-7

Internet

https://doi.org/10.1186/s12885-023-11428-7

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