PRKRA promotes pancreatic cancer progression by upregulating MMP1 transcription via the NF-κB pathway

PRKRA promotes pancreatic cancer progression by upregulating MMP1 transcription via the NF-κB pathway

Objective: Pancreatic cancer (PC) is highly malignant, but the underlying mechanisms of cancer progression remain unclear. PRKRA is involved in cellular stress response, but its role in PC was unknown. Methods: The expression of PRKRA between normal and tumor tissues were compared, and the prognosti...

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Bibliographic Details
Main Authors: Jiangdong Qiu, Mengyu Feng, Gang Yang, Dan Su, Fangyu Zhao, Yueze Liu, Jinxin Tao, Wenhao Luo, Taiping Zhang
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Heliyon
Subjects:
PRKRA
Pancreatic cancer
Organoids
Progression
Biomarker
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402304402X

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http://www.sciencedirect.com/science/article/pii/S240584402304402X

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