Natural Compounds Targeting Cancer-Associated Fibroblasts against Digestive System Tumor Progression: Therapeutic Insights

Natural Compounds Targeting Cancer-Associated Fibroblasts against Digestive System Tumor Progression: Therapeutic Insights

Cancer-associated fibroblasts (CAFs) are critical for cancer occurrence and progression in the tumor microenvironment (TME), due to their versatile roles in extracellular matrix remodeling, tumor–stroma crosstalk, immunomodulation, and angiogenesis. CAFs are the most abundant stromal component in th...

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Bibliographic Details
Main Authors: Kuan-Jung Chiu, Hsin-Ying Clair Chiou, Chi-Han Huang, Pin-Chun Lu, Hui-Ru Kuo, Jiunn-Wei Wang, Ming-Hong Lin
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Biomedicines
Subjects:
tumor microenvironment
cancer-associated fibroblasts (CAFs)
digestive system cancers
gastrointestinal cancer
natural products
Online Access:https://www.mdpi.com/2227-9059/10/3/713

Internet

https://www.mdpi.com/2227-9059/10/3/713

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