A New Series of Indeno[1,2-<i>c</i>]pyrazoles as EGFR TK Inhibitors for NSCLC Therapy

A New Series of Indeno[1,2-<i>c</i>]pyrazoles as EGFR TK Inhibitors for NSCLC Therapy

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death throughout the world. Due to the shortcomings of traditional chemotherapy, targeted therapies have come into prominence for the management of NSCLC. In particular, epidermal growth factor receptor (EGFR) tyrosine kinase...

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Bibliographic Details
Main Authors: Ahmet Özdemir, Halilibrahim Ciftci, Belgin Sever, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita, Mehlika Dilek Altıntop
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
anticancer activity
apoptosis
epidermal growth factor receptor
indenopyrazoles
microwave-assisted synthesis
non-small cell lung cancer
Online Access:https://www.mdpi.com/1420-3049/27/2/485

Internet

https://www.mdpi.com/1420-3049/27/2/485

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