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Changes of MODY signal pathway genes in the endoplasmic reticulum stress in INS-1-3 cells.

Changes of MODY signal pathway genes in the endoplasmic reticulum stress in INS-1-3 cells.

<h4>Objective</h4>Metabolic disturbances induce endoplasmic reticulum stress (ERS) in pancreatic beta cells. This study aims to investigate whether a common pathway exists in the ERS induced by various chemicals, including high levels of glucose and palmitate in INS-1-3 cells.<h4>M...

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Bibliographic Details
Main Authors: Yanan Dong, Shirui Li, Wenhui Zhao, Yanlei Wang, Tingting Ge, Jianzhong Xiao, Yukun Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0198614/1/pone.0198614.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210223%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210223T031246Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0198614/1/pone.0198614.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210223%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210223T031246Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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