Improved Kidney Allograft Function after Early Conversion of Fast IR-Tac Metabolizers to LCP-Tac

Fast tacrolimus (Tac) metabolism is associated with a more rapid decline of renal function after renal transplantation (RTx). Because the pharmacokinetics of LCP-Tac (LCPT) and immediate-release Tac (IR-Tac) differ, we hypothesized that switching from IR-Tac to LCPT in kidney transplant recipients w...

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Bibliographic Details
Main Authors: Gerold Thölking, Filiz Tosun-Koç, Ulrich Jehn, Raphael Koch, Hermann Pavenstädt, Barbara Suwelack, Stefan Reuter
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Journal of Clinical Medicine
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Online Access:https://www.mdpi.com/2077-0383/11/5/1290