Longitudinal Multi-Parametric Liquid Biopsy Approach Identifies Unique Features of Circulating Tumor Cell, Extracellular Vesicle, and Cell-Free DNA Characterization for Disease Monitoring in Metastatic Breast Cancer Patients

Longitudinal Multi-Parametric Liquid Biopsy Approach Identifies Unique Features of Circulating Tumor Cell, Extracellular Vesicle, and Cell-Free DNA Characterization for Disease Monitoring in Metastatic Breast Cancer Patients

Dynamics of mRNA from circulating tumor cells (CTCs), mRNA from extracellular vesicles (EVs), and cell-free DNA (cfDNA) were assessed to examine the relevance of a longitudinal multi-parametric liquid biopsy strategy. Eighteen milliliters of blood was drawn from 27 hormone receptor-positive and huma...

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Bibliographic Details
Main Authors: Corinna Keup, Vinay Suryaprakash, Markus Storbeck, Oliver Hoffmann, Rainer Kimmig, Sabine Kasimir-Bauer
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cells
Subjects:
multi-parametric
multi-modal
multi-analyte
follow-up
serial sampling
gene expression
Online Access:https://www.mdpi.com/2073-4409/10/2/212

Internet

https://www.mdpi.com/2073-4409/10/2/212

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