Protective efficacy of a Zika purified inactivated virus vaccine candidate during pregnancy in marmosets

Abstract Zika virus (ZIKV) infection during pregnancy poses significant threats to maternal and fetal health, leading to intrauterine fetal demise and severe developmental malformations that constitute congenital Zika syndrome (CZS). As such, the development of a safe and effective ZIKV vaccine is a...

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Bibliographic Details
Main Authors: In-Jeong Kim, Olga Gonzalez, Michael P. Tighe, Paula A. Lanthier, Madeline J. Clark, Kelsey L. Travis, Timothy C. Low-Beer, Kathleen G. Lanzer, Derek T. Bernacki, Frank M. Szaba, Rafael A. De La Barrera, Vincent Dussupt, Letzibeth Mendez-Rivera, Shelly J. Krebs, Corinna N. Ross, Stephanie D. Mdaki, Kathleen M. Brasky, Donna Layne-Colon, Suzette D. Tardif, Stephen J. Thomas, Kayvon Modjarrad, Marcia A. Blackman, Jean L. Patterson
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-00824-0