Myriocin‐induced adaptive laboratory evolution of an industrial strain of Saccharomyces cerevisiae reveals its potential to remodel lipid composition and heat tolerance

Summary The modification of lipid composition allows cells to adjust membrane biophysical properties in response to changes in environmental temperature. Here, we use adaptive laboratory evolution (ALE) in the presence of myriocin, a sphingolipid (SLs) biosynthesis inhibitor, to remodel the lipid pr...

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Bibliographic Details
Main Authors: Francisca Randez‐Gil, Jose A. Prieto, Alejandro Rodríguez‐Puchades, Josefina Casas, Vicente Sentandreu, Francisco Estruch
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Microbial Biotechnology
Online Access:https://doi.org/10.1111/1751-7915.13555