Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1

Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1

Atherosclerotic plaque preferentially develops in arterial curvatures and branching regions, where endothelial cells constantly experience disturbed blood flow. By contrast, the straight arteries are generally protected from plaque formation due to exposure of endothelial cells to vaso-protective la...

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Bibliographic Details
Main Authors: Fangfang Yang, Yunpeng Zhang, Juanjuan Zhu, Jin Wang, Zhitong Jiang, Chuanrong Zhao, Qianru Yang, Yu Huang, Weijuan Yao, Wei Pang, Lili Han, Jing Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
endothelial permeability
shear stress
MALAT1
Nesprins
β-catenin
endothelial cells
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00647/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00647/full

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