Curcumin pre-treatment may protect against mitochondrial damage in LRRK2-mutant Parkinson's disease and healthy control fibroblasts

Curcumin pre-treatment may protect against mitochondrial damage in LRRK2-mutant Parkinson's disease and healthy control fibroblasts

Mitochondrial dysfunction has been proposed as one of the pathobiological underpinnings in Parkinson's disease. Environmental stressors, such as paraquat, induce mitochondrial dysfunction and promote reactive oxygen species production. Targeting oxidative stress pathways could prevent mitochond...

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Bibliographic Details
Main Authors: Shameemah Abrahams, Hayley C. Miller, Carl Lombard, Francois H. van der Westhuizen, Soraya Bardien
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Biochemistry and Biophysics Reports
Subjects:
Turmeric
Mitochondrial function
Paraquat
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821001291

Internet

http://www.sciencedirect.com/science/article/pii/S2405580821001291

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