Molecular basis of interactions between CaMKII and α-actinin-2 that underlie dendritic spine enlargement

Ca2+/calmodulin-dependent protein kinase II (CaMKII) is essential for long-term potentiation (LTP) of excitatory synapses that is linked to learning and memory. In this study, we focused on understanding how interactions between CaMKIIα and the actin-crosslinking protein α-actinin-2 underlie long-la...

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Bibliographic Details
Main Authors: Ashton J Curtis, Jian Zhu, Christopher J Penny, Matthew G Gold
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/85008