Low CD10 mRNA expression identifies high-risk ductal carcinoma in situ (DCIS).

Low CD10 mRNA expression identifies high-risk ductal carcinoma in situ (DCIS).

PURPOSE: Optimal management of breast ductal carcinoma in situ (DCIS) is controversial, and many patients are still overtreated. The local death of myoepithelial cells (MECs) is believed to be a pre-requisite to tumor invasion. We thus hypothesized that loss of CD10 expression, a MEC surface peptida...

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Bibliographic Details
Main Authors: Jérôme Toussaint, Virginie Durbecq, Sevilay Altintas, Valérie Doriath, Ghizlane Rouas, Marianne Paesmans, Philippe Bedard, Benjamin Haibe-Kains, Wiebren A Tjalma, Denis Larsimont, Martine Piccart, Christos Sotiriou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2938371?pdf=render

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http://europepmc.org/articles/PMC2938371?pdf=render

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