Moving fluid biomarkers for Alzheimer’s disease from research tools to routine clinical diagnostics
Abstract Four fluid-based biomarkers have been developed into diagnostic tests for Alzheimer’s disease (AD) pathology: the ratio of 42 to 40 amino acid-long amyloid β, a marker of plaque pathology; total-tau and phosphorylated tau, markers of AD-related changes in tau metabolism and secretion; and n...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-02-01
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Series: | Molecular Neurodegeneration |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13024-021-00430-x |