Moving fluid biomarkers for Alzheimer’s disease from research tools to routine clinical diagnostics

Abstract Four fluid-based biomarkers have been developed into diagnostic tests for Alzheimer’s disease (AD) pathology: the ratio of 42 to 40 amino acid-long amyloid β, a marker of plaque pathology; total-tau and phosphorylated tau, markers of AD-related changes in tau metabolism and secretion; and n...

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Bibliographic Details
Main Authors: Henrik Zetterberg, Kaj Blennow
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Molecular Neurodegeneration
Subjects:
Online Access:https://doi.org/10.1186/s13024-021-00430-x