Atorvastatin improves plaque stability in ApoE-knockout mice by regulating chemokines and chemokine receptors.

It is well documented that statins protect atherosclerotic patients from inflammatory changes and plaque instability in coronary arteries. However, the underlying mechanisms are not fully understood. Using a previously established mouse model for vulnerable atherosclerotic plaque, we investigated th...

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Bibliographic Details
Main Authors: Peng Nie, Dandan Li, Liuhua Hu, Shuxuan Jin, Ying Yu, Zhaohua Cai, Qin Shao, Jieyan Shen, Jing Yi, Hua Xiao, Linghong Shen, Ben He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4016207?pdf=render