Apigenin and Rutaecarpine reduce the burden of cellular senescence in bone marrow stromal stem cells

Apigenin and Rutaecarpine reduce the burden of cellular senescence in bone marrow stromal stem cells

IntroductionOsteoporosis is a systemic age-related disease characterized by reduced bone mass and microstructure deterioration, leading to increased risk of bone fragility fractures. Osteoporosis is a worldwide major health care problem and there is a need for preventive approaches.Methods and resul...

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Main Authors: Dalia Ali, Meshail Okla, Sarah Abuelreich, Radhakrishnan Vishnubalaji, Nicholas Ditzel, Rimi Hamam, Justyna M. Kowal, Ahmed Sayed, Abdullah Aldahmash, Nehad M. Alajez, Moustapha Kassem
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Endocrinology
Subjects:
bone marrow stromal stem cells
osteoblasts
senescence
aging
antioxidants
osteoporosis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1360054/full

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https://www.frontiersin.org/articles/10.3389/fendo.2024.1360054/full

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