Optimizing microbiome sequencing for small intestinal aspirates: validation of novel techniques through the REIMAGINE study

Optimizing microbiome sequencing for small intestinal aspirates: validation of novel techniques through the REIMAGINE study

Abstract Background The human small intestine plays a central role in the processes of digestion and nutrient absorption. However, characterizations of the human gut microbiome have largely relied on stool samples, and the associated methodologies are ill-suited for the viscosity and low microbial b...

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Bibliografiska uppgifter
Huvudupphovsmän: Gabriela Guimaraes Sousa Leite, Walter Morales, Stacy Weitsman, Shreya Celly, Gonzalo Parodi, Ruchi Mathur, Rashin Sedighi, Gillian M. Barlow, Ali Rezaie, Mark Pimentel
Materialtyp: Artikel
Språk:English
Publicerad: BMC 2019-11-01
Serie:BMC Microbiology
Ämnen:
Small intestine
Microbiome
Mucus layer
Methodology optimization
Microbial culture
16S rRNA gene sequencing
Länkar:http://link.springer.com/article/10.1186/s12866-019-1617-1

Internet

http://link.springer.com/article/10.1186/s12866-019-1617-1

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