Geometry of the Gene Expression Space of Individual Cells.

There is a revolution in the ability to analyze gene expression of single cells in a tissue. To understand this data we must comprehend how cells are distributed in a high-dimensional gene expression space. One open question is whether cell types form discrete clusters or whether gene expression for...

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Bibliographic Details
Main Authors: Yael Korem, Pablo Szekely, Yuval Hart, Hila Sheftel, Jean Hausser, Avi Mayo, Michael E Rothenberg, Tomer Kalisky, Uri Alon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4498931?pdf=render