Identifying and evaluating clinical subtypes of Alzheimer’s disease in care electronic health records using unsupervised machine learning

Abstract Background Alzheimer’s disease (AD) is a highly heterogeneous disease with diverse trajectories and outcomes observed in clinical populations. Understanding this heterogeneity can enable better treatment, prognosis and disease management. Studies to date have mainly used imaging or cognitio...

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Bibliographic Details
Main Authors: Nonie Alexander, Daniel C. Alexander, Frederik Barkhof, Spiros Denaxas
Format: Article
Language:English
Published: BMC 2021-12-01
Series:BMC Medical Informatics and Decision Making
Subjects:
Online Access:https://doi.org/10.1186/s12911-021-01693-6