Identifying targetable metabolic dependencies across colorectal cancer progression

Identifying targetable metabolic dependencies across colorectal cancer progression

Colorectal cancer (CRC) is a multi-stage process initiated through the formation of a benign adenoma, progressing to an invasive carcinoma and finally metastatic spread. Tumour cells must adapt their metabolism to support the energetic and biosynthetic demands associated with disease progression. As...

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Bibliografische gegevens
Hoofdauteurs: Danny N. Legge, Tracey J. Collard, Ewelina Stanko, Ashley J. Hoskin, Amy K. Holt, Caroline J. Bull, Madhu Kollareddy, Jake Bellamy, Sarah Groves, Eric H. Ma, Emma Hazelwood, David Qualtrough, Borko Amulic, Karim Malik, Ann C. Williams, Nicholas Jones, Emma E. Vincent
Formaat: Artikel
Taal:English
Gepubliceerd in: Elsevier 2024-12-01
Reeks:Molecular Metabolism
Onderwerpen:
Colorectal cancer
Oncometabolism
Asparagine
Asparagine synthetase
Adenoma
Adenocarcinoma
Online toegang:http://www.sciencedirect.com/science/article/pii/S2212877824001686

Internet

http://www.sciencedirect.com/science/article/pii/S2212877824001686

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