Brain tumours repurpose endogenous neuron to microglia signalling mechanisms to promote their own proliferation

Previously we described direct cellular interactions between microglia and AKT1+ brain tumour cells in zebrafish (Chia et al., 2018). However, it was unclear how these interactions were initiated: it was also not clear if they had an impact on the growth of tumour cells. Here, we show that neoplasti...

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Bibliographic Details
Main Authors: Kelda Chia, Marcus Keatinge, Julie Mazzolini, Dirk Sieger
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/46912