Placental DNA Methylation Abnormalities in Prenatal Conotruncal Heart Defects

Objective: This study aims to characterize the abnormal changes in placental DNA methylation associated with conotruncal heart defects (CTDs) and the level of methylation as epigenetic biomarkers for CTDs detection.Methods: This was a prospective study involving 28 fetuses diagnosed with CTDs in the...

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Bibliographic Details
Main Authors: Jingjing Liu, Yuduo Wu, Hairui Sun, Xiaowei Liu, Xiaoyan Gu, Ying Zhao, Ye Zhang, Jiancheng Han, Yihua He
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.878063/full