Surveillance of fluoroquinolones resistance in rifampicin-susceptible tuberculosis in eastern China with whole-genome sequencing-based approach

Surveillance of fluoroquinolones resistance in rifampicin-susceptible tuberculosis in eastern China with whole-genome sequencing-based approach

BackgroundLeveraging well-established DNA-level drug resistance mechanisms, whole-genome sequencing (WGS) has emerged as a valuable methodology for predicting drug resistance. As the most effective second-line anti-tuberculosis (anti-TB) drugs, fluoroquinoloness (FQs) are generally used to treat mul...

Full description

Bibliographic Details
Main Authors: Yang Che, Yewei Lu, Yelei Zhu, Tianfeng He, Xiangchen Li, Junli Gao, Junshun Gao, Xiaomeng Wang, Zhengwei Liu, Feng Tong
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Microbiology
Subjects:
fluoroquinolones resistance
drug resistance
whole-genome sequencing
rifampicin-susceptible tuberculosis
hetero-resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1413618/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2024.1413618/full

Similar Items